Marathon Rotary Club

Wednesday, 12:15pm Meeting at the Marathon Yacht Club

To attain a formal diagnostic position.

Speaking at the 26th ECNP Congress Professor Suzanne Dickson, neuroscientist from the Institute of Physiology and Neuroscience, Sahlgrenska Academy at the University of Gothenburg, Sweden, said, the launch of 'addictive disorders' enables classification of behavioural addiction for the very first time, for instance with pathological gambling, but this will not apply to meals addiction. Although there could be neurobiological and medical overlaps between 'addictive-like' overeating and chemical related and addictive disorders, a significant difference is that’s that food usage, unlike alcoholic beverages, cocaine, or gambling or internet video gaming behaviours, is essential for survival.Our study shows that the production of peroxynitrite causes cell dysfunction and death by activating or ‘turning on’ a cellular tension pathway, termed the ER stress response pathway. Although activation of this pathway is known as to be protective, prolonged or severe ER stress induced by peroxynitrite can lead to devastating cytotoxic effects. In addition to these findings, we have reported previously that activation of this cellular tension pathway causes changes in lipid irritation and metabolism, conditions that also accelerate atherosclerosis. Predicated on these findings, Dr. Austin and his study team are actually developing novel ways of block this cellular tension pathway in the hopes of inhibiting cell dysfunction and death, which can ultimately lead to the advancement of atherosclerosis and cardiovascular disease.